Select Page

Anti-LC3 mAb for My select sampler set

M152-3MS
Antibody
20 uL

$170.84

DATA SHEET

This LC3 monoclonal antibody of 20 µL is validated for multiple applications (FCM, IC, IH, IP, WB) and has over 25 citations.

More information about LC3 and autophagy can be found in our Blog. In addition you may download our Autophagy Pathway Poster.

TargetLC3
Product TypeAntibody
ApplicationFCM, ICC, IHC, IP, WB
ClonalityMonoclonal
ConjugateUnlabeled
IsotypeIgG1 κ
ImmunogenRecombinant Human LC3 (MAP1LC3B: 1-120 a.a.)
Host SpeciesMouse
Species ReactivityHuman, Hamster, Mouse, Rat
Formulation40 µg IgG in 20 µL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Research AreaAutophagy
Description/Background

Macroautophagy mediates the bulk degradation of cytoplasmic components. These components are delivered to lysosomes via autophagosomes. The rat microtubule-associated protein 1 light chain 3 (LC3), a homologue of yeast Atg8 (Aut7/Apg8), localizes to autophagosomal membranes after post-translational modifications. The C-terminal fragment of LC3 is cleaved immediately following synthesis to yield a cytosolic form called LC3-I. A subpopulation of LC3-I is further converted to an autophagosome-associating form, LC3-II. This antibody can detect both forms of LC3.

Storage Temperature-20°C
ProtocolsFCM, ICC, IHC, IP, WB
Clone Number4.00E+12
Concentration2 mg/mL
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
M152-3MS
Antibody
20 uL

$170.84

Related Products

Related Content

SIGN UP