Anti-CD52 (CAMPATH-1) (Mouse) mAb (Monoclonal Antibody)

Name: Anti-CD52 (CAMPATH-1) (Mouse) mAb (Monoclonal Antibody)
SKU: D204-3
Price: 303.19 USD
Availability: InStock

Code D204-3

Product Type Antibody

Size 100 μg/100 μL

$303.19

Monoclonal antibody targeting CAMPATH-1/CD52 for FCM, IPP.

Target	CAMPATH-1/CD52
Product Type	Antibody
Application	FCM, IP
Clonality	Monoclonal
Conjugate	Unlabeled
Isotype	IgG2a
Immunogen	Transgenic mouse spleen cell IL-2R alpha
Host Species	Rat
Species Reactivity	Mouse
Formulation	100 µg IgG in 100 µL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Research Area	Apoptosis
Description/Background	CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa; however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.
Storage Temperature	-20°C
Protocols	FCM, IP
Clone Number	BTG-2G
Concentration	1 mg/mL
Regulatory Statement	For Research Use Only. Not for use in diagnostic procedures.