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Anti-CD52 (CAMPATH-1) (Mouse) mAb-PE (Monoclonal Antibody)

D204-5
Antibody
50 tests

$330.75

DATA SHEET

Monoclonal antibody conjugated to PE of 50 tests targeting CAMPATH-1/CD52 for FCM.

TargetCAMPATH-1/CD52
Product TypeAntibody
ApplicationFCM
ClonalityMonoclonal
ConjugatePE
IsotypeIgG2a
ImmunogenTransgenic mouse spleen cell IL-2Ralpha
Host SpeciesRat
Species ReactivityMouse
Formulation 50 tests in 1 mL volume of PBS containing 1% BSA and 0.09% NaN3. *Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain.
Research AreaImmunology, Cell Biology
Description/BackgroundCAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa; however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.
Storage Temperature4°C
ProtocolsFCM
Clone NumberBTG-2G
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
D204-5
Antibody
50 tests

$330.75

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