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Anti-SynCAM (TSLC1/CADM1) (Human) mAb

CM005-3
Antibody
100 μg/100 μL

$429.84

DATA SHEET

Monoclonal antibody targeting SynCAM/TSLC1 for FCM.

TargetSynCAM/TSLC1
Product TypeAntibody
ApplicationFCM
ClonalityMonoclonal
ConjugateUnlabeled
IsotypeIgY
ImmunogenRecombinant SynCAM/Fc fusion protein
Host SpeciesChicken
Species ReactivityHuman
Formulation100 µg IgG in 100 µL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Research AreaNeuroscience
Description/Background

SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1 (tumor suppressor in lung cancer-1), SgIGSF, or CADM1, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily involved in intracellular adhesion and synapse formation. The majority of SynCAM is localized to synaptic sites where it initiates synaptic assembly and synapse differentiation throughout the central nervous system. SynCAM also mediates the cellular adhesion of spermatogenic cells to Sertoli cells and mast cells to fibroblasts.

Storage Temperature-20°C
ProtocolsFCM
Clone Number9D2
Concentration1 mg/mL
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CM005-3
Antibody
100 μg/100 μL

$429.84

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