Anti-SynCAM (TSLC1/CADM1) mAb-PE (Monoclonal Antibody)
Monoclonal Antibody targeting SynCAM (TSLC1/CADM1) conjugated to PE.
| Target | SynCAM (TSLC1/CADM1) |
|---|---|
| Product Type | Antibody |
| Application | FCM |
| Clonality | Monoclonal |
| Conjugate | Unlabeled |
| Isotype | IgY |
| Immunogen | Recombinant SynCAM-Fc fusion protein |
| Host Species | Chicken |
| Species Reactivity | Human |
| Formulation | PBS containing 1% BSA and 0.09% NaN3 *Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain. |
| Research Area | Cancer, Neuroscience |
| Description/Background | SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1 (tumor suppressor in lung cancer-1), SgIGSF, or CADM1, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily involved in intracellular adhesion and synapse formation. The majority of SynCAM is localized to synaptic sites where it initiates synaptic assembly and synapse differentiation throughout the central nervous system. SynCAM also mediates the cellular adhesion of spermatogenic cells to Sertoli cells and mast cells to fibroblasts. |
| Storage Temperature | This antibody solution is stable for one year from the date of purchase when stored at 4°C. |
| Protocols | FCM |
| Clone Number | 3E1 |
| Source | Purified IgY from hybridoma supernatant |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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