Anti-p62 C-terminal (Human) pAb (Polyclonal Antibody)
Polyclonal Antibody of 100 µl targeting p62 for IC, IH, IP, WB.
| Target | p62 |
|---|---|
| Product Type | Antibody |
| Application | IC, IH, IP, WB |
| Clonality | Polyclonal |
| Conjugate | Unlabeled |
| Isotype | Affinity Purified Ig |
| Immunogen | KLH conjugated human p62 C-terminus peptide |
| Host Species | Guinea Pig |
| Species Reactivity | Human, Hamster, Mouse, Rat |
| Formulation | PBS containing 50% Glycerol (pH 7.2). No preservative is contained. |
| Research Area | Autophagy |
| Description/Background | p62/SQSTM1 interacts with various molecular groups such as RIP, TRAF6, ERK, aPKCs, and poly-ubiquitin through PB1 domain, Zn finger domain, and UBA domain. This protein directly interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency. |
| Storage Temperature | This antibody solution is stable for one year from the date of purchase when stored at -20°C. |
| Protocols | IC, IH, IP, WB |
| Source | Purified Ig from Guinea Pig serum |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
