Anti-CD13 (Mouse) mAb (Monoclonal Antibody)

CD13 is a myeloid differentiation molecule expressed on committed myeloid progenitors,
granulocytes, monocytes, and leukemic cells of myeloid origin. It is also expressed on non-hematopoietic cells including fibroblasts, renal proximal tubule, and small intestine brush-border membrane. The gene for CD13 has recently been cloned the cDNA sequence shows that CD13 is the metalloprotease aminopeptidase N. Biochemical studies have shown that CD13 is a 150 kDa glycoprotein, which exists as a 130 kDa intracellular precursor form. This 130 kDa precursor molecule is posttranslationally modified in the Golgi apparatus to produce the 150 kDa mature cell surface form of the molecule.