Anti-Mouse CD3 APC-Cyanine7 (Monoclonal Antibody)
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex.
The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.
| Target | CD3 |
|---|---|
| Product Type | Antibody |
| Application | FCM |
| Clonality | Monoclonal |
| Conjugate | APC-Cyanine7 |
| Isotype | Rat IgG2a, kappa |
| Formulation | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| Research Area | Immunology, Flow Cytometry |
| Storage Temperature | Product should be kept at 2-8°C and protected from prolonged exposure to light. |
| Protocols | FCM |
| Clone Number | 17A2 |
| Concentration | 0.2 mg/mL |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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