Select Page

Anti-CD11b (Human/Mouse) mAb-PE-Cy7 (Monoclonal Antibody)

This product is only available in the US
25 µg



The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.

M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.

Application Notes:

The antibody has been analyzed for quality through the flow cytometric analysis of the relevant cell type. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ug per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product TypeAntibody
IsotypeIgG2b ĸ
Host SpeciesRat
Species ReactivityHuman, Mouse
FormulationPhosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Research AreaImmunology, Angiogenesis, Flow Cytometry, Innate Immunity
Storage TemperatureThe product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clone NumberM1/70
Concentration0.2 mg/mL
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
25 µg


Related Content