Anti-Atg8 (Filamentous fungi) pAb
This antibody can detect pro-Atg8, Atg8 and Atg8-PE
Target | Atg8 (Filamentous fungi) |
---|---|
Product Type | Antibody |
Application | WB |
Clonality | Polyclonal |
Conjugate | Unlabeled |
Isotype | Affinity Purified Ig |
Immunogen | Recombinant protein, corresponding to amino acids 1-116 of rice blast fungus MGG_01062 (Atg8) |
Host Species | Rabbit |
Formulation | PBS containing 50% Glycerol (pH 7.2). No preservative is contained |
Research Area | Cancer, Immunology, Autophagy |
Description/Background | Autophagy is a well-known degradation system, induced by nutrient starvation, in which cytoplasmic components and organelles are digested via vacuoles/lysosomes.The fungus Atg8, a homologue of yeast Atg8 (Aut7/Apg8), localizes to autophagosomal membranes after post-translational modifications. The C-terminal region of pro-Atg8 is cleaved immediately following synthesis by Atg4 to yield a cytosolic form, Atg8. A subpopulation of Atg8 is further converted to an autophagosome-associating form, Atg8-PE. This antibody can detect pro-Atg8, Atg8 and Atg8-PE. |
Storage Temperature | This antibody solution is stable for one year from the date of purchase when stored at -20°C. |
Protocols | WB |
Source | Purified Ig from rabbit serum |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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