QuickSwitch™ HLA-A*02:01 Quant Monomer Kit
The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
Please use this link for access to the QuickSwitch™ Peptide Exchange Calculator to check your binding affinity.
| Product Type | Monomer |
|---|---|
| Application | FCM |
| Class | Class I |
| Species Reactivity | Human |
| Allele | HLA-A*02:01 |
| Peptide Sequence | Custom |
| Research Area | Immunology, Immune Monitoring |
| Protocols | FCM |
| Specificity | Custom |
| Description/Background | <p>The QuickSwitch™ Quant Monomer Kit utilizes a patented technique for exchanging up to ten peptides on an MHC Class I Monomer. After performing your peptide exchange, you can tetramerize the monomers and add your own conjugate. Create your own custom Class I MHC Tetramers in your own lab.</p> |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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