Tetramer/BV421 – Mafa-A1*063 SIV nef RM9 (RPKVPLRTM)

DATA SHEET

Nonhuman primates (NHP) resemble humans in multiple ways including similarities in genomics,  immunogenetics, and age-related changes in immune function. These characteristics are critical to the establishment of a relevant model in which to conduct preclinical studies to optimize the efficacy and safety of  therapeutic approaches. Importantly, NHPs are vital preclinical models for viruses as viral infections are frequently associated with the same pathologies. Hence, NHPs are immune models to study viral vaccine efficacy and antiviral therapeutic safety and efficacy and to understand aspects of viral pathogenesis. Over numerous preclinical studies for human viral diseases, NHPs have demonstrated to be a beneficial benchmark for investigating human viral infections.