| Target | Hemoglobin F |
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| Product Type | Antibody |
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| Application | IHC |
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| Clonality | Polyclonal |
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| Conjugate | Unlabeled |
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| Isotype | Affinity Purified Ig |
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| Immunogen | KLH conjugated synthetic peptide, CLTSLGDAIKH (corresponding to amino acid residues 69-78 of human hemoglobin, gamma A) |
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| Host Species | Rabbit |
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| Species Reactivity | Human |
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| Formulation | PBS containing 1% BSA and 0.09% NaN3
*Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain. |
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| Research Area | Cancer, Immunology |
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| Description/Background | Human hemoglobin is consists from heterotetramer of two alpha chains and two non-alpha chains,and each poly peptide chain binds one heme. 3 types of hemoglobin, HbA(α2β2), HbA2(α2δ2) and HbF(α2γ2), presents in normal adults. The synthesis of HemoglobinA(HbA) increases after the birth , whereas Hemoglobin F (HbF) rapidly declines to extremely about 1% or less of the whole by the age of 1 year. HbF-containing cells are minor erythrocytes in normal adults, however, detects in fetus and in patients with aplastic anemia, MDS, hemoglobinopathies, and malignancies affecting the erythropoietic system. |
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| Storage Temperature | This antibody solution is stable for one year from the date of purchase when stored at 4°C. |
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| Protocols | IHC |
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| Source | Purified IgG from rabbit serum |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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