Anti-Mesothelin (Mouse) mAb (Monoclonal Antibody)
Monoclonal antibody of 100 µL targeting Mesothelian for FCM.
| Target | Mesothelian |
|---|---|
| Product Type | Antibody |
| Application | FCM |
| Clonality | Monoclonal |
| Conjugate | Unlabeled |
| Isotype | IgG2a |
| Immunogen | Mouse hemangioblast-like cell line LO cells |
| Host Species | Rat |
| Species Reactivity | Mouse |
| Formulation | 100 µg IgG in 100 µL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Research Area | Immunology, Apoptosis |
| Description/Background | Mesothelin (MSLN) is a GPI-linked cell surface glycoprotein expressed in the mesothelial lining of the body cavities and in mullerian duct epithelium related cancer cells (ovarian, pancreatic cancer, mesothelioma). Both human and mouse mesothelin bind to ovarian cancer antigen CA125/MUC16 with high affinity, mediating cell attachment in vitro, suggesting that mesothelin may facilitate ovarian cancer metastasis. |
| Storage Temperature | -20°C |
| Protocols | FCM |
| Clone Number | B35 |
| Concentration | 1 mg/mL |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
