CircuLex PCSK9 D374Y in culture medium
PCSK9 binds to the LDL receptor in vitro and in vitro. Human PCSK9 D374Y containing a C-terminal His-tag, expressed in HEK 293 cells. Binding capability to EGF-AB domain of LDL receptor was confirmed by using CircuLex PCSK9-LDLR in vitro Binding Assay Kit (CY-8150). The PCSK9 D374Y in culture medium might be used for LDLR degradation assay on HepG2 cell. Unused PCSK9 D374Y in culture medium should be stored at -70°C.
| Target | PCSK9 |
|---|---|
| Product Type | Recombinant Protein |
| Formulation | Supplied frozen in DMEM, 10 % FCS and appropriate antibiotics in sterile condition. |
| Research Area | Metabolism |
| Storage Temperature | -70°C |
| Concentration | 50 µg (20 µg/mL x 1.25 mL x 2) |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |