Phospho-AKT1-T308+AKT2-T309+AKT3-T305 Rabbit pAb
| Target | Akt |
|---|---|
| Product Type | Antibody |
| Application | WB |
| Isotype | IgG |
| Immunogen | A synthetic phosphorylated peptide around T308 of human AktAKT1 (NP_005154.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.05% proclin300,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. |
| Protocols | WB |
| Molecular Weight | 48kDa/55kDa/51kDa/54kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |