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Phospho-Beclin 1-Ser90 Rabbit pAb

This product is only available in the US
CNAP1254P
Antibody
100 µl

$450.00

DATA SHEET

TargetBECN1
Product TypeAntibody
ApplicationWB
IsotypeIgG
ImmunogenA synthetic phosphorylated peptide around S90 of human Beclin 1 (NP_003757.1).
Host SpeciesRabbit
Species ReactivityHuman, Mouse
FormulationPBS with 0.05% proclin300,50% glycerol
Research AreaCancer, Immunology
Description/Background

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

ProtocolsWB
Molecular Weight52kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNAP1254P
Antibody
100 µl

$450.00

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