Phospho-TDP-43/TARDB-S409/S410 Rabbit pAb
| Target | TARDBP |
|---|---|
| Product Type | Antibody |
| Application | WB |
| Isotype | IgG |
| Immunogen | A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDB (NP_031401.1). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Formulation | PBS with 0.05% proclin300,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer’s disease, Pick’s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. |
| Protocols | WB |
| Molecular Weight | 45kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |