Phospho-RIPK1/RIP-S166 Rabbit pAb
Target | Phospho-RIPK1/RIP-S166 |
---|---|
Product Type | Antibody |
Application | WB |
Clonality | Loading Control Antibody |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | A synthetic phosphorylated peptide around S166 of human RIPK1/RIP (NP_003795.2). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse |
Formulation | PBS with 0.05% Proclin300,50% glycerol |
Research Area | Cancer |
Description/Background | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. |
Storage Temperature | Store at -20℃ |
Protocols | WB |
Molecular Weight | 76kDa |
Purification | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |