Phospho-CGAS-S291 Rabbit pAb
This product is only available in the US
CNAP1176T
Antibody
100 µl
$450.00
Target | CGAS |
---|---|
Product Type | Antibody |
Application | WB |
Isotype | IgG |
Immunogen | A synthetic phosphorylated peptide around S291 of mouse CGAS (NP_775562.2). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse |
Formulation | PBS with 0.01% thimerosal,50% glycerol |
Research Area | Cancer, Immunology, Epigenetics |
Description/Background | This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. |
Protocols | WB |
Components | 58kDa |
Molecular Weight | 58kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
This product is only available in the US
CNAP1176T
Antibody
100 µl
$450.00