Phospho-Histone H3-S28 Rabbit pAb
| Target | H3C1 |
|---|---|
| Product Type | Antibody |
| Application | ICC, IF, WB |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | A synthetic phosphorylated peptide around S28 of human Histone H3 (NP_003520.1). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Other (Wide Range), Rat |
| Formulation | PBS with 0.01% thimerosal,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |
| Protocols | ICC, IF, WB |
| Molecular Weight | 16kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |