Phospho-PLC gamma 1 (PLCG1)-S1248 Rabbit pAb
| Target | PLCG1 |
|---|---|
| Product Type | Antibody |
| Application | IHC (P), WB |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | A synthetic phosphorylated peptide around S1248 of human PLC gamma 1 (PLCG1) (NP_002651.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.01% thimerosal,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer’s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Protocols | IHC (P), WB |
| Molecular Weight | 149kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |