Select Page

Phospho-PKC (pan) (gamma)-T514 Rabbit pAb

This product is only available in the US
CNAP0613S
Antibody
100 µl

$450.00

DATA SHEET

TargetPRKCA/PRKCB/PRKCD/PRKCE/PRKCG/PRKCH/PRKCQ
Product TypeAntibody
ApplicationWB
ClonalityPolyclonal
IsotypeIgG
ImmunogenA synthetic phosphorylated peptide around T514 of human PKC (pan) (gamma)PRKCA (NP_002728.2).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.02% sodium azide,50% glycerol
Research AreaCancer, Immunology
Description/Background

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

ProtocolsWB
Molecular Weight59-67kDa/74-83kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNAP0613S
Antibody
100 µl

$450.00

SIGN UP