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Phospho-β-Catenin-S552 Rabbit pAb

This product is only available in the US
CNAP0579S
Antibody
100 µl

$450.00

DATA SHEET

TargetCTNNB1
Product TypeAntibody
ApplicationWB
ClonalityPolyclonal
IsotypeIgG
ImmunogenA synthetic phosphorylated peptide around S552 of human beta Catenin (NP_001091679).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.02% sodium azide,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background<p>The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This Protein A Affinity purificationcts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.</p>
ProtocolsWB
Molecular Weight85kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNAP0579S
Antibody
100 µl

$450.00

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