ACVRL1 Rabbit mAb
Target | ACVRL1 |
---|---|
Product Type | Antibody |
Application | ICC, IF, WB |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 404-503 of human ACVRL1 (P37023). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
Research Area | Cancer, Immunology, Metabolism |
Description/Background | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
Protocols | ICC, IF, WB |
Molecular Weight | 56kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |