| Target | LRP8 |
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| Product Type | Antibody |
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| Application | WB |
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| Clonality | Monoclonal |
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| Isotype | IgG |
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| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 864-963 of human ApoER2/LRP8 (Q14114). |
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| Host Species | Rabbit |
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| Species Reactivity | Human, Mouse, Rat |
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| Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
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| Research Area | Cancer, Immunology, Metabolism |
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| Description/Background | <p>This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport Protein A Affinity purificationpolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.</p> |
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| Protocols | WB |
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| Molecular Weight | 106kDa |
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| Purity | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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