Target | YWHAZ |
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Product Type | Antibody |
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Application | IF/ICC, IHC (P), WB |
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Clonality | Polyclonal |
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Conjugate | unconjugated |
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Isotype | IgG |
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Immunogen | A synthetic peptide corresponding to a sequence within amino acids 190 to the C-terminus of human YWHAZ (NP_003397.1). |
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Host Species | Rabbit |
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Species Reactivity | Human, Mouse, Rat |
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Formulation | PBS with 0.09% Sodium azide,50% glycerol |
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Research Area | Cancer, Epigenetics |
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Description/Background | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. |
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Storage Temperature | Store at -20℃ |
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Protocols | IF/ICC, IHC (P), WB |
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Molecular Weight | 28kDa |
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Purification | Affinity purification |
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Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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