[KO Validated] Integrin alpha 2 (ITGA2/CD49b) Rabbit pAb
| Target | ITGA2 |
|---|---|
| Product Type | Antibody |
| Application | ICC, IF, IHC (P), WB |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Integrin alpha 2 (ITGA2/CD49b) (NP_002194.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.05% proclin300,50% glycerol |
| Research Area | Cancer, Immunology, Metabolism |
| Description/Background | This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this Protein A Affinity purificationre found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. |
| Protocols | ICC, IF, IHC (P), WB |
| Molecular Weight | 129kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |