PDZK1 Rabbit pAb
| Target | PDZK1 |
|---|---|
| Product Type | Antibody |
| Application | WB |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDZK1 (NP_001188254.1). |
| Host Species | Rabbit |
| Species Reactivity | Mouse |
| Formulation | PBS with 0.02% sodium azide,50% glycerol |
| Research Area | Cancer, Immunology, Metabolism |
| Description/Background | This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Protocols | WB |
| Molecular Weight | 57kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |