| Target | SF3A3 |
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| Product Type | Antibody |
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| Application | IF/ICC, IHC (P), WB |
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| Clonality | Polyclonal |
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| Conjugate | unconjugated |
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| Isotype | IgG |
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| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3 (NP_006793.1). |
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| Host Species | Rabbit |
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| Species Reactivity | Human, Mouse, Rat |
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| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
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| Research Area | CancerEpigenetics |
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| Description/Background | This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. |
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| Storage Temperature | Store at -20℃ |
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| Protocols | IF/ICC, IHC (P), WB |
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| Molecular Weight | 59kDa |
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| Purification | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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