| Target | NAE1 |
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| Product Type | Antibody |
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| Application | WB |
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| Clonality | Polyclonal |
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| Conjugate | unconjugated |
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| Isotype | IgG |
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| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NAE1 (NP_003896.1). |
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| Host Species | Rabbit |
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| Species Reactivity | Human, Mouse, Rat |
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| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
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| Research Area | CancerEpigenetics |
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| Description/Background | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
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| Storage Temperature | Store at -20℃ |
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| Protocols | WB |
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| Molecular Weight | 60kDa |
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| Purification | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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