| Target | FTO |
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| Product Type | Antibody |
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| Application | ICC, IF, IHC (P), IP, WB |
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| Clonality | Monoclonal |
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| Isotype | IgG |
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| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FTO (Q9C0B1). |
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| Host Species | Rabbit |
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| Species Reactivity | Human |
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| Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
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| Research Area | Cancer, Immunology, Metabolism |
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| Description/Background | <p>This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.</p> |
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| Protocols | ICC, IF, IHC (P), IP, WB |
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| Molecular Weight | 58kDa |
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| Purity | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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