STING/TMEM173 Rabbit pAb
| Target | Recombinant fusion protein containing a sequence corresponding to amino acids 150-379 of human STING/TMEM173 (NP_938023.1). |
|---|---|
| Product Type | Antibody |
| Application | IF/ICC, IHC (P), IP, WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 150-379 of human STING/TMEM173 (NP_938023.1). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
| Research Area | CancerEpigenetics |
| Description/Background | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
| Storage Temperature | Store at -20℃ |
| Protocols | IF/ICC, IHC (P), IP, WB |
| Molecular Weight | 42kDa |
| Purification | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |