[KO Validated] SMARCB1/SNF5 Rabbit mAb
| Target | SMARCB1 |
|---|---|
| Product Type | Antibody |
| Application | IHC (P), WB |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SMARCB1/SNF5 (NP_003064.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.05% proclin300,0.05% BSA,50% glycerol |
| Research Area | Cancer, Immunology, Epigenetics |
| Description/Background | The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. |
| Protocols | IHC (P), WB |
| Molecular Weight | 44kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |