| Target | DNMT3B |
|---|
| Product Type | Antibody |
|---|
| Application | IF/ICC, WB |
|---|
| Clonality | Polyclonal |
|---|
| Conjugate | unconjugated |
|---|
| Isotype | IgG |
|---|
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 345-475 of human DNMT3B (Q9UBC3). |
|---|
| Host Species | Rabbit |
|---|
| Species Reactivity | Human, Mouse, Rat |
|---|
| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
|---|
| Research Area | CancerEpigenetics |
|---|
| Description/Background | This protien enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1). |
|---|
| Storage Temperature | Store at -20℃ |
|---|
| Protocols | IF/ICC, WB |
|---|
| Molecular Weight | 96kDa |
|---|
| Purification | Affinity purification |
|---|
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
|---|
