| Target | DiMethyl-Histone H3-K79 |
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| Product Type | Antibody |
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| Application | ChIP, ChIP-seq, IF/ICC, IHC (P), IP, WB |
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| Clonality | Polyclonal |
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| Conjugate | unconjugated |
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| Isotype | IgG |
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| Immunogen | A synthetic dimethylated peptide around K79 of human Histone H3 (NP_003520.1). |
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| Host Species | Rabbit |
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| Species Reactivity | Human, Mouse, Other (Wide Range), Rat |
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| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
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| Research Area | CancerEpigenetics |
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| Description/Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
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| Storage Temperature | Store at -20℃ |
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| Protocols | ChIP, ChIP-seq, IF/ICC, IHC (P), IP, WB |
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| Molecular Weight | 16kDa |
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| Purification | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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