Leptin Receptor Rabbit mAb

Name: Leptin Receptor Rabbit mAb
SKU: CNA19076S
Price: 450.00 USD
Availability: InStock

Code CNA19076S

Product Type Antibody

Size 100 µl

THIS ITEM HAS BEEN DISCONTINUED

Target	LEPR
Product Type	Antibody
Application	IHC (P), WB
Clonality	Monoclonal
Isotype	IgG
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human Leptin Receptor (P48357).
Host Species	Rabbit
Species Reactivity	Human, Mouse, Rat
Formulation	PBS with 0.02% sodium azide,0.05% BSA,50% glycerol
Research Area	Cancer, Immunology, Metabolism
Description/Background	<p>The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).</p>
Protocols	IHC (P), WB
Molecular Weight	132kDa
Concentration	0.5 mg/mL
Purity	Affinity purification
Regulatory Statement	For Research Use Only. Not for use in diagnostic procedures.