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Integrin alpha V (ITGAV/CD51) Rabbit mAb

CNA19071P
Antibody
100 µl

$450.00

DATA SHEET

TargetITGAV
Product TypeAntibody
ApplicationFCM, IHC (P), WB
ClonalityMonoclonal
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 949-1048 of human Integrin alpha V (ITGAV/CD51) (NP_002201.2).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.05% proclin300,0.05% BSA,50% glycerol
Research AreaCancer, Immunology
Description/Background

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

ProtocolsFCM, IHC (P), WB
Molecular Weight116kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA19071P
Antibody
100 µl

$450.00

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