HDAC1 Mouse mAb
| Target | HDAC1 |
|---|---|
| Product Type | Antibody |
| Application | ChIP, IHC (P), WB |
| Clonality | Monoclonal |
| Isotype | IgG1kappa |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (Q13547). |
| Host Species | Mouse |
| Species Reactivity | Human, Mouse |
| Formulation | PBS with 0.01% thimerosal,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor Protein A Affinity purificationnd this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
| Protocols | ChIP, IHC (P), WB |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |