NF-kB p65/RelA Mouse mAb
Target | RELA |
---|---|
Product Type | Antibody |
Application | IF/ICC, WB |
Clonality | Monoclonal |
Conjugate | unconjugated |
Isotype | IgG2b,Kappa |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 450-551 of human NF-kB p65/RelA (Q04206). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Formulation | PBS with 0.05% Proclin300,50% glycerol |
Research Area | Cancer, Epigenetics, Metabolism |
Description/Background | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |
Storage Temperature | Store at -20℃ |
Protocols | IF/ICC, WB |
Molecular Weight | 60kDa |
Purification | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |