CEACAM5 Mouse mAb
| Target | CEACAM5 |
|---|---|
| Product Type | Antibody |
| Application | IHC (P), IP, WB |
| Clonality | Monoclonal |
| Isotype | IgG1kappa |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 35-685 of human CEACAM5. |
| Host Species | Mouse |
| Species Reactivity | Human |
| Formulation | PBS with 0.01% thimerosal,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. |
| Protocols | IHC (P), IP, WB |
| Molecular Weight | 77kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |