CYP11A1 Rabbit pAb
| Target | CYP11A1 |
|---|---|
| Product Type | Antibody |
| Application | IF/ICC, IHC (P), WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CYP11A1 (NP_000772.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.05% Proclin300,50% glycerol |
| Research Area | Cancer, Metabolism |
| Description/Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. |
| Storage Temperature | Store at -20℃ |
| Protocols | IF/ICC, IHC (P), WB |
| Molecular Weight | 60kDa |
| Purification | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |