Select Page

C-Reactive Protein (CRP) Rabbit pAb

CNA15659T
Antibody
100 µl

$450.00

DATA SHEET

TargetCRP
Product TypeAntibody
ApplicationWB
ClonalityPolyclonal
Conjugateunconjugated
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-50 of human C-Reactive Protein (CRP) (NP_000558.2).
Host SpeciesRabbit
Species ReactivityMouse
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology, Metabolism
Description/Background<p>The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component Protein A Affinity purificationnd pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection.</p>
ProtocolsWB
Molecular Weight23kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA15659T
Antibody
100 µl

$450.00

SIGN UP