| Target | CDH5 |
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| Product Type | Antibody |
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| Application | IHC (P), WB |
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| Clonality | Polyclonal |
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| Conjugate | unconjugated |
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| Isotype | IgG |
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| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 621-784 of human VE Cadherin (NP_001786.2). |
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| Host Species | Rabbit |
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| Species Reactivity | Human, Mouse |
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| Formulation | PBS with 0.05% Proclin300,50% glycerol |
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| Research Area | Cancer |
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| Description/Background | This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. |
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| Storage Temperature | Store at -20℃ |
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| Protocols | IHC (P), WB |
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| Molecular Weight | 88kDa |
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| Purification | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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