Glycophorin C (GYPC) Rabbit mAb
Target | GYPC |
---|---|
Product Type | Antibody |
Application | IHC (P), WB |
Clonality | Monoclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 49-128 of human Glycophorin C (GYPC) (P04921). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
Research Area | Cancer, Immunology |
Description/Background | Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. |
Protocols | IHC (P), WB |
Molecular Weight | 14kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |