Select Page

Smad3 Rabbit pAb

This product is only available in the US
CNA11471S
Antibody
100 µl

$450.00

DATA SHEET

TargetSmad3  
Product TypeAntibody
ApplicationWB
Conjugateunconjugated
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 150-250 of human Smad3 (NP_005893.1).
Host SpeciesRabbit
Species ReactivityRat
FormulationPBS with 0.02% sodium azide,50% glycerol
Research AreaCancer, Immunology, Metabolism
Description/Background

The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3.

ProtocolsWB
Components48kDa
Molecular Weight48kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA11471S
Antibody
100 µl

$450.00

SIGN UP