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TFE3 Rabbit mAb

This product is only available in the US
CNA0548S
Antibody
100 µl

$450.00

DATA SHEET

TargetTFE3
Product TypeAntibody
ApplicationIHC (P), WB
Conjugateunconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 191-440 of human TFE3 (P19532).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.02% sodium azide,0.05% BSA,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background

This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

ProtocolsIHC (P), WB
Components62kDa
Molecular Weight62kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA0548S
Antibody
100 µl

$450.00

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