| Target | BAK1 |
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| Product Type | Antibody |
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| Application | ICC, IF, IP, WB |
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| Clonality | Polyclonal |
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| Conjugate | unconjugated |
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| Isotype | IgG |
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| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bak (NP_001179.1). |
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| Host Species | Rabbit |
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| Species Reactivity | Human, Mouse, Rat |
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| Formulation | PBS with 0.01% thimerosal,50% glycerol |
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| Research Area | Cancer, Immunology, Metabolism |
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| Description/Background | <p>The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This Protein A Affinity purificationlso interacts with the tumor suppressor P53 after exposure to cell stress.</p> |
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| Protocols | ICC, IF, IP, WB |
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| Molecular Weight | 23kDa |
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| Purity | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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