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Bak Rabbit pAb

This product is only available in the US
CNA0204T
Antibody
100 µl

$450.00

DATA SHEET

TargetBAK1
Product TypeAntibody
ApplicationICC, IF, IP, WB
Conjugateunconjugated
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bak (NP_001179.1).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology, Metabolism
Description/Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This Protein A Affinity purificationlso interacts with the tumor suppressor P53 after exposure to cell stress.

ProtocolsICC, IF, IP, WB
Components23kDa
Molecular Weight23kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA0204T
Antibody
100 µl

$450.00

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