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ATF4 Rabbit pAb

This product is only available in the US
CNA0201S
Antibody
100 µl

$450.00

DATA SHEET

TargetATF4
Product TypeAntibody
ApplicationWB
Conjugateunconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human ATF4 (NP_001666.2).
Host SpeciesRabbit
Species ReactivityHuman
FormulationPBS with 0.02% sodium azide,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

ProtocolsWB
Components39kDa
Molecular Weight39kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA0201S
Antibody
100 µl

$450.00

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