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GDF15 Rabbit pAb

This product is only available in the US
CNA0185T
Antibody
100 µl

$450.00

DATA SHEET

TargetGDF15
Product TypeAntibody
ApplicationICC, IF, IHC (P), IP, WB
Conjugateunconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human GDF15 (NP_004855.2).
Host SpeciesRabbit
Species ReactivityHuman
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology
Description/Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.

ProtocolsICC, IF, IHC (P), IP, WB
Components34kDa
Molecular Weight34kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA0185T
Antibody
100 µl

$450.00

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